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Exam Code: ABMM
Exam Questions: 205
American Board of Medical Microbiology (ABMM)
Updated: 20 Feb, 2026
Question 1

A clinical isolate of Klebsiella pneumoniae from a patient with a refractory urinary tract infection exhibits resistance to carbapenems (imipenem, meropenem, ertapenem). PCR analysis reveals the presence of the blaKPC gene. Which of the following enzymatic mechanisms is responsible for this resistance?

Options :
Answer: A

Question 2

A clinical laboratory manager is implementing a new automated blood culture system. Which aspect is LEAST likely to be part of the initial verification/validation process before clinical use?

Options :
Answer: C

Question 3

A patient with HIV infection and a CD4+ T-cell count below 50 cells/µL develops a progressive neurological illness characterized by confusion, motor deficits, and seizures. Brain MRI reveals multiple white matter lesions without mass effect. PCR of the CSF is positive for JC virus. Thepathogenesis of this condition, progressive multifocal leukoencephalopathy (PML), involves: 

Options :
Answer: B

Question 4

Which biosafety level (BSL) is required for clinical laboratory work involving the propagation (culture) of Coccidioides immitis/posadasii? 

Options :
Answer: C

Question 5

A clinical microbiology laboratory is using flow cytometry to analyze lymphocyte subsets in a patient with suspected immunodeficiency. Which of the following cell surface markers is typically used to identify helper T cells?

Options :
Answer: B

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