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Exam Code: PCAT
Exam Questions: 285
Pharmacy College Admission Test
Updated: 15 Jan, 2026
Question 1

A lab requires 0.76 L of a solution. How many 100 mL vials must be used in the lab?

Options :
Answer: B

Question 2

Sickle cell disease (SCD) affects millions of individuals worldwide, and the Sickle Cell Disease Association of
America estimates that 70,000 to 100,000 individuals have SCD and 3 million individuals have the sickle cell
trait. While SCD is known to primarily affect individuals of African American descent, individuals from South
America, the Caribbean, Central America, the Middle East, and the Mediterranean can also have SCD or the
SCD trait. SCD is estimated to affect 1 in 500 African American infants, and 1 in 12 African Americans are
estimated to have the sickle cell trait. SCD is characterized by episodes of acute and chronic pain. By
increasing awareness about SCD and promoting patient education, health care professionals can help patients
and their families cope with SCD and better manage the associated pain. Recurring episodes of acute and/or
severe pain are hallmarks of SCD. SCD pain can often be debilitating, and episodes of pain vary from patient to
patient in both frequency and intensity. SCD pain can be classified as acute, chronic, or mixed. At some point,
most SCD patients experience episodes of pain often referred to as vaso-occlusive crisis (sickle cell crisis), the
duration of which may range from hours to days. Some patients seldom have a sickle cell crisis, while others
may experience crises several times a year. Some episodes may be so severe that hospitalization is warranted
to manage the pain. An acute pain event is the most common type of pain, and the onset is typically abrupt. It is
often the result of an ischemic tissue injury, which is due to the occlusion of microvascular beds by sickled
erythrocytes during an acute crisis. Acute pain episodes can also be triggered by factors including extreme
temperature changes, changes in altitude, physical and emotional stress, illnesses, infections, dehydration, cold
climates, menstruation, and fatigue. Chronic pain is pain that lasts for 3 to 6 months or longer. Chronic pain
often results from the destruction of bones, joints, and visceral organs due to recurrent crises. Sources of
chronic sickle cell pain include aseptic necrosis, leg ulcerations, and osteomyelitis. Unfortunately, acute and
chronic pain associated with SCD are commonly undertreated or inappropriately managed due to patient fear of
potential addiction and adverse effects. Many studies report that some health care professionals are also
concerned about the potential for addiction. When appropriate, pharmacologic management of SCD pain may
involve the use of 3 major pharmacologic classes: nonopioids, opioids, and adjuvants.
Out of this group, which of the following demographic is the LEAST likely to have SCD?

Options :
Answer: D

Question 3

Jim has 10 apples and he gives 7 to Bill. Now Bill has 3 times as many apples as Jim had. How many apples
did Bill have to begin with?

Options :
Answer: C

Question 4

Since 1997, the American Heart Association (AHA) has attempted to increase awareness about cardiovascular
disease (CVD) among women. Fortunately, great progress has been made to educate individuals about CVD
and its consequences. According to the AHA’s 2011 Guidelines for Prevention of Cardiovascular Disease in
Women, the misconception that CVD is a “man’s disease” has been somewhat disproved, as awareness
among the general public increased from 30% in 1997 to 54% in 2009. Unfortunately, CVD continues to be the
leading cause of death in the United States for both men and women. Since 1984, the number of deaths related
to CVD in women exceeded those in men. In the United States, CVD death rates among women aged 35 to 54
years appear to be increasing by 1% annually, which is most likely attributable to the escalating obesity
epidemic. According to the AHA, even though CVD is the number 1 cause of death among women, only 13% of
women perceive CVD as a health threat. CVD is responsible for more deaths among women than the next 3
leading causes of death combined, including all forms of cancer. Due to the ongoing prevalence of CVD,
increasing awareness and understanding of CVD, especially among the female population, is still a top priority
for many health care professionals. As one of the most accessible health care professionals, pharmacists are in
a pivotal position to educate and inform their patients of the risks associated with CVD, possible drug therapies,
and preventive measures. The AHA has set a goal for 2020 to improve cardiovascular health in all Americans
by 20%, while reducing deaths from CVD and stroke by 20%. According to the American Heart Association, in
the United States a woman dies of some form of CVD every minute and more than 1 in 3 females have some
form of CVD. Studies have demonstrated that gender differences may play an important role in the diagnosis,
treatment, and prevention of CVD. Unfortunately, many women may not always recognize the warning signs
and symptoms of a heart attack because they sometimes appear more subtle when compared with those
typically experienced by men. Results from a study of 515 women who had heart attacks report that 43% did
not experience any type of chest pain or pressure during the heart attack. Although the classic symptoms
include chest pain, tingling in the left arm, sweating, and shortness of breath, women may also experience
some “atypical” symptoms, such as extreme fatigue, nausea, dizziness, indigestion, vomiting, and pain in the
neck or back. By learning and recognizing the warning signs, women can take a proactive approach to their
cardiovascular health and get treatment earlier to prevent further complications.
Throughout the passage, it is implied that which of the following will lead to fewer deaths resulting from CVD?

Options :
Answer: B

Question 5

In which non-membranous compartment are ribosomes made in a eukaryotic cell?

Options :
Answer: C

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